Effects of Phenylephrine and Prazosin on Axial Movement of the Rat Incisor and Arterial Blood Pressure

スポンサーリンク

概要

• 論文の詳細を見る

• We investigated the dose-response effects of phenylephrine and antagonistic effects of prazosin on axial movement of the rat incisor and arterial blood pressure. Phenylephrine caused a temporal extrusive tooth movement and an increase in blood pressure at all doses. With increasing phenylephrine doses, the maximum extrusive tooth movement and maximum increase in blood pressure were enhanced. The maximum extrusive tooth movement and increase in blood pressure induced by phenylephrine were markedly suppressed after pretreatment with prazosin. These results suggested that extrusive tooth movement is closely related to the rise in blood pressure due to stimulation of vascular α1-receptors.

• 社団法人 日本薬理学会の論文

著者

• Yamaguchi Shizuyo

  Department Of Pharmacology School Of Dental Medicine Tsurumi University

• Yamaguchi Shizuyo

  Departments Of Pharmacology School Of Dental Medicine Tsurumi University

• Ohyama Nami

  Department Of Dental Anesthesiology School Of Dental Medicine Tsurumi University

• Ohyama Nami

  Departments Of Dental Anesthesiology School Of Dental Medicine Tsurumi University

関連論文

• Mechanical properties of the periodontal ligament in scorbutic mutant rat incisors
• Preventive Effects of Nitroglycerin Buccal Tablets to Increase of Blood Pressure during Dental Treatment
• Effects of Phenylephrine and Prazosin on Axial Movement of the Rat Incisor and Arterial Blood Pressure
• The blocking effects of tolazoline and propranolol on axial movements of incisor teeth and on changes in arterial blood pressure induced by adrenaline in rats

スポンサーリンク