Evaluation of Ready-to-use Liquid Reagents for Clinical Chemistry in Laboratory Animals
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概要
- 論文の詳細を見る
We evaluated the ready-to-use liquid reagents for clinical chemistry (6 tests), to assess their suitability for use in the toxicology laboratory setting. Hitachi 736 automated analyzer was used for the analyses. The evaluation included the following studies: Precision, Linearity, Effects of interference substances such as hemolytic hemoglobin, bilirubin, turbidity to the analytical values and correlation to the solid reagents, which are prepared each time they are needed. The precision and linearity data were within the reagents specifications. Results of comparison of the liquid reagents and the solid reagents in analyzing plasma samples of rats, dogs and monkeys were generally good except for a bias in results for GOT and GPT, regardless of the animal species tested. It is concluded that these types of liquid reagents can be used in clinical pathology examinations in animal studies.
- 社団法人 日本実験動物学会の論文
著者
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MATSUZAWA Toshiaki
Safety Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
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TABATA HAJIME
Safety Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
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Tabata Hajime
Safety Research Laboratories Yamanouchi Pharmaceutical Co. Ltd.
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NAGAMATSU Nami
Safety Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
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SAKAZUME Masashi
Safety Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
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Matsuzawa Toshiaki
Safety Research Laboratories Yamanouchi Pharmaceutical Co. Ltd.
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Matsuzawa Toshiaki
Safety Research Laboratories Of Yamanouchi Pharmaceutical Co. Ltd.
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Nagamatsu Nami
Safety Research Laboratories Yamanouchi Pharmaceutical Co. Ltd.
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Sakazume Masashi
Safety Research Laboratories Yamanouchi Phamaceutical Co. Ltd.
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Sakazume Masashi
Safety Research Laboratories Yamanouchi Pharmaceutical Co. Ltd.
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