A Rhino Mutant Originating in KK Mice
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概要
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In 1991, several hairless offspring were found in our black haired KK (KK-C) mouse colony. This mutant, provisionally naming KK-rhino mouse was clinicopathologically and histopathologically investigated in a chronological manner. KK-rhino has a hairless trait and wrinkled and pimpled skin, which resemble the characteristics of the so-called rhino mouse. It was presumed from a preliminary mating examination that the trait of the KK-rhino mutant might be manifested by the [hrrh] gene. Other properties of this mutant might be inherited from the maternal KK-C line. KK-rhino mouse is a unique mouse strain which has two quite different traits, "rhino" and "diabetes".
- 社団法人 日本実験動物学会の論文
著者
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KUME Eisuke
Lead Optimization Research Laboratory, Tanabe Seiyaku Co., Ltd.
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Yamada Tamotsu
Marugo Research Service Co. Ltd.
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Kume E
Tanabe Seiyaku Co. Ltd. Saitama Jpn
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Kume Eisuke
Lead Optimization Research Laboratory Tanabe Seiyaku Co. Ltd.
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IWASAKI Hitoshi
Lead Optimization Research Laboratory, Tanabe Seiyaku Co. Ltd.
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Iwasaki Hitoshi
Lead Optimization Research Laboratory Tanabe Seiyaku Co. Ltd.
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- A Rhino Mutant Originating in KK Mice