Symptomatic Hypocalcemia in a Patient with Latent Hypoparathyroidism and Breast Carcinoma with Bone Metastasis Following Administration of Pamidronate

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概要

• 論文の詳細を見る

• Pamidronate is an effective drug used not only in patients with tumor-associated hypercalcemia, but also in normocalcemic patients with metastatic bone disease to relieve pains. We describe a 39-year-old normocalcemic patient with subclinical hypoparathyroidism and bone metastasis due to breast carcinoma. Following parenteral administration of 60 mg pamidronate, the corrected serum level of calcium decreased from 2.12 mmol/l (=8.9 mg/dl) to 1.42 mmol/l (5.7 mg/dl), accompanied with carpal pedal spasm. The present case indicates that the hypocalcemia due to latent hypoparathyroidism was compensated by extensive osteolysis due to bone metastasis, and that overt hypocalcemia may develop after intravenous administration of pamidronate in such a patient.(Internal Medicine 37: 396-397, 1998)

• 社団法人 日本内科学会の論文

著者

• Piskin Ozden

  Dokuz Eylul University Medical Faculty Department Of Internal Medicine

• COMLEKCI Abdurrahman

  Dokuz Eylul University, Medical Faculty Division of Endocrinology and Metabolism

• BIBEROGLU Sevinc

  Dokuz Eylul University, Medical Faculty Division of Endocrinology and Metabolism

• HEKIMSOY Zeliha

  Dokuz Eylul University, Medical Faculty Division of Endocrinology and Metabolism

• OKAN Inci

  Dokuz Eylul University, Medical Faculty Department of Internal Medicine

• SEKEROGLU Binnaz

  Dokuz Eylul University, Medical Faculty Division of Oncology

• ALAKAVUKLAR Mehmet

  Dokuz Eylul University, Medical Faculty Division of Oncology

• Sekeroglu Binnaz

  Dokuz Eylul University Medical Faculty Division Of Oncology

• Okan Inci

  Dokuz Eylul University Medical Faculty Department Of Internal Medicine

• Alakavuklar Mehmet

  Dokuz Eylul University Medical Faculty Division Of Oncology

• Comlekci Abdurrahman

  Dokuz Eylul University Medical Faculty Division Of Endocrinology And Metabolism

• Hekimsoy Zeliha

  Dokuz Eylul University Medical Faculty Division Of Endocrinology And Metabolism

• Biberoglu Sevinc

  Dokuz Eylul University Medical Faculty Division Of Endocrinology And Metabolism

関連論文

• Symptomatic Hypocalcemia in a Patient with Latent Hypoparathyroidism and Breast Carcinoma with Bone Metastasis Following Administration of Pamidronate
• Elevated Thrombin Activatable Fibrinolysis Inhibitor (TAFI) Antigen Levels in Overt and Subclinical Hypothyroid Patients Were Reduced by Levothyroxine Replacement

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