Histamine Poisoning after Ingestion of Spoiled Raw Tuna in a Patient Taking Isoniazid

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概要

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• An 83-year-old woman taking isoniazid (INH) suddenly developed a headache, palpitations, and skin eruptions with itching while eating raw tuna. The symptoms were compatible with those of histamine intoxication. When given fresh raw tuna to eat, no such reactions were evoked in this patient. The episode was speculated to be due to two conditions; eating spoiled raw tuna and at the same time being on a course of INH, a potent histaminase inhibitor. We should therefore be aware of the possible adverse effects due to the interactions between drugs and foods.(Internal Medicine 36:198-200, 1997)

• 社団法人 日本内科学会の論文

著者

• Mizushima Yutaka

  The First Department Of Internal Medicine Toyama Medical And Pharmaceutical University

• Morinaga Shinichi

  The Toyama Jounan Spa Hospital

• Hirata Hitoshi

  The Toyama Jounan Spa Hospital

• KAWASAKI Akira

  the Department of Internal Medicine, Saiseikai Takaoka Hospital

• SUZUKI Shinji

  the Toyama Jounan Spa Hospital

• Kawasaki Akira

  The Department Of Internal Medicine Saiseikai Takaoka Hospital

• Mizushima Yutaka

  The First Department Of Internal Medicine

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