Cimetidine in the Treatment of Porphyria Cutanea Tarda
スポンサーリンク
概要
- 論文の詳細を見る
The efficacy of the H2 receptor antagonist, cimetidine, in the treatment of a patient with porphyria cutanea tarda (PCX) was evaluated. After administration of cimetidine for 2 weeks, urinary excretion of uroporphyrin (UP) and coproporphyrin (CP) was significantly decreased. Urinary porphyrin levels remained low even after the cessation of cimetidine for 1 week. Although the readministration of cimetidine did not decrease porphyrin excretion, skin lesions were markedly improved, and serum γ-glutamyl transpeptidase (GGT), aminotransferases and serum ferritin decreased to the normal range. These results suggest that, in addition to efficacy in the treatment of acute intermittent porphyria (AIP) and erythropoietic protoporpyria (EPP), cimetidine is effective in the treatment of PCT.(Internal Medicine 35: 717-719, 1996)
- 社団法人 日本内科学会の論文
著者
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KONDO Masao
Department of Nutrition and Biochemistry, National Institute of Public Health
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Horie Yutaka
Second Department Of Internal Medicine Faculty Of Medicine Tottori University
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Kawasaki H
Tottori Univ. Yonago Jpn
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OKANO Jun-ichi
the Second Department of Internal Medicine
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HORIE Yutaka
the Second Department of Internal Medicine
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KAWASAKI Hironaka
the Second Department of Internal Medicine
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Tanaka Keiko
Second Department Of Internal Medicine Faculty Of Medicine Tottori University
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Sassa Shigeru
The Rockefeller University
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Okano Junichi
Second Department Of Internal Medicine Faculty Of Medicine Tottori University
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TANAKA Keiko
the Department of Dermatology, Tottori University School of Medicine
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OKANO Junichi
the Second Department of Internal Medicine
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OHGI Nagako
the Second Department of Internal Medicine
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YAMAMOTO Shinichirou
The Division of Gastroenterology, Kawasaki Medical School
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KONDO Masao
the Department of Nutrition and Biochemistry, the Institute of Public Health
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Kondo Masao
Department Of Nutrition And Biochemistry National Institute Of Public Health
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Tanaka Kiwamu
Second Department Of Internal Medicine Faculty Of Medicine Tottori University
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Yamamoto Shinichirou
The Division Of Gastroenterology Kawasaki Medical School
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Tanaka Keiko
The Department Of Dermatology Tottori University School Of Medicine
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