Outbreak of Chinese Herb Nephropathy in Japan: Are There Any Differences from Belgium?
スポンサーリンク
概要
- 論文の詳細を見る
Objective The purpose of this article was to study and clarify the features of Chinese herb nephropathy (CHN) in Japan. Patients and Methods The subjects consisted of patients diagnosed as having CHN in Saiseikai Nakatsu Hospital and of those reported in the literature in Japan. We investigated the clinical and histological features of CHN patients in Japan and compared them with the Belgian cases. Results The remarkable differences were as follows: (1) high prevalence in males compared with Belgian cases, (2) Fanconi syndrome was found in most cases, (3) no patients had malignant tumors in the urinary tract. In addition, the ascribed Chinese medicines in Japan were divided into three groups: Tenshin-toki-shigyaku-ka-gosyuyu-syokyo-to, Boui-ougi-to, and others. Conclusion CHN in Japan has some characteristics distinguished from Belgian nephropathy. One hypothesis is a susceptibility to aristolochic acids (AAs), which is considered to be a causative agent, may be different among races. Another is that there could be some other toxic substances affecting the clinical findings although they are not identified at present. Further studies must be undertaken to clarify these differences.(Internal Medicine 40: 296-300, 2001)
- 社団法人 日本内科学会の論文
著者
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KUWAHARA Takashi
Department of Nephrology, Saiseikai Nakatsu Hospital
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Nishida Ritsuo
The Division Of Applied Life Sciences Laboratory Of Chemical Ecology Kyoto University
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Goto Masahisa
The Department Of Nephrology Osaka Saiseikai Nakatsu Hospital
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Kuwahara Takashi
Department Of Nephrology Saiseikai Nakatsu Hospital
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Tanaka Atsuo
Department Of Nephrology Osaka Saiseikai Nakatsu Hospital
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TANAKA Atsuo
the Department of Nephrology, Osaka Saiseikai Nakatsu Hospital
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YOSHIDA Toshiyuki
the Department of Nephrology, Osaka Saiseikai Nakatsu Hospital
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KOSHIKAWA Masao
the Department of Nephrology, Osaka Saiseikai Nakatsu Hospital
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KUWAHARA Takashi
the Department of Nephrology, Osaka Saiseikai Nakatsu Hospital
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Tanaka Atsuo
The Department Of Nephrology Saiseikai Nakatsu Hospital
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Kuwahara Takashi
Department Of Nephrology Osaka Saiseikai Nakatsu Hospital
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Kuwahara Takashi
The Department Of Nephrology Saiseikai Nakatsu Hospital
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Yoshida Toshiyuki
The Department Of Nephrology Osaka Saiseikai Nakatsu Hospital
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