High Fever, Renal Failure, Disseminated Intravascular Coagulation and Myelodysplasia Accompanied with Enhanced Angiogenesis Possibly due to Overexpression of Vascular Endothelial Growth Factor
スポンサーリンク
概要
- 論文の詳細を見る
A 44-year-old woman suffered from recurrent fever, edema and fatigue. Laboratory data revealed renal dysfunction, low proteinemia, disseminated intravascular coagulation (DIG) and myelodysplasia. A renal and lymph node biopsy showed a marked angiogenesis. Serum levels of vascular endothelial growth factor (VEGF), and interleukin (IL)-6 were markedly increased, suggesting a pathogenesis related to VEGF-induced angiogenesis. The symptoms were remitted after treatment with cyclosporin A. No evidence of solid tumors, malignant lymphoma, Castlemans disease or POEMS (polyneuropathy, organomegaly, endocrine disorder, M-proteinemia and skin change) syndrome, reported to induce a high serum VEGF level, was obtained. This case may have involved an unknown mechanism which induced an overexpression of VEGF and IL-6.(Internal Medicine 39: 570-575, 2000)
- 社団法人 日本内科学会の論文
著者
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Ryu Tomiko
The Department Of Internal Medicine Social Insurance Chuo General Hospital
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Miura Yasusada
The Department Of Internal Medicine Social Insurance Chuo General Hospital
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Miura Yasusada
Department Of Internal Medicine Social Insurance Chuo General Hospital
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Tokuda Hitoshi
The Department Of Internal Medicine Social Insurance Chuo General Hospital
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Kitamura S
Department Of Pathology Social Insurance Chuo General Hospital
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Masuo Masatoshi
Department Of Medicine Social Insurance Chuo General Hospital
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KITAMURA Shigehiro
Pathology Division, Social Insurance Central Hospital
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Kitamura Shigehiro
Pathology Division Social Insurance Central Hospital
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Miura Yasusada
The Department Of Hematology
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Murata Hiroshi
Pharmaceutical Research Laboratory Kirin Brewery Co. Ltd.
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Murata Hiroshi
The Department Of Internal Medicine Social Insurance Chuo General Hospital
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YOSHIMOTO Hiroshi
the Department of Internal Medicine, Social Insurance Chuo General Hospital
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MASUO Masatoshi
the Department of Internal Medicine, Social Insurance Chuo General Hospital
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TOYAMA Junko
the Department of Internal Medicine
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Yoshimoto Hiroshi
Department Of Medicine Social Insurance Chuo General Hospital
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