Sacoidosis with Membranous Nephropathy and Granulomatous Interstitial Nephritis

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概要

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• A 49-year-old woman, who had been diagnosed as sarcoidosis based on bilateral hilar lymphadenopathy and lung biopsy, presented increased serum creatinine and calcium concentrations. Renal biopsy showed the presence of interstitial nephritis with non-caseating epithelioid granuloma and focal membranous transformation. Therapy with prednisolone was effective in normalizing serum creatinine, serum calcium, serum angiotensin converting enzyme, and urine β2 microglobulin, but these abnormalities reappeared after rapid withdrawal of prednisolone. This is a rare case of sarcoidosis manifested by both membranous nephropathy and granulomatous interstitial nephritis, and indicates the necessity of long-term treatment of corticosteroid.(Internal Medicine 38: 882-886, 1999)

• 社団法人 日本内科学会の論文

著者

• Toda Takayuki

  The Department Of Internal Medicine Hokushin General Hospital

• KIMOTO Shigeaki

  the Department of Internal Medicine,Hokushin General Hospital

• NISHIO Yasuhide

  the Department of Internal Medicine,Hokushin General Hospital

• EHARA Takasi

  the First Department of pathology,Shinshu University School of Medicine

• SASAKI Sei

  the Second Department of Internal Medicine,Tokyo Medical and Dental University

• Sasaki Sei

  The Second Department Of Internal Medicine Tokyo Medical And Dental University

• Ehara Takasi

  The First Department Of Pathology Shinshu University School Of Medicine

• Nishio Yasuhide

  The Department Of Internal Medicine Hokushin General Hospital

• Kimoto Shigeaki

  The Department Of Internal Medicine Hokushin General Hospital

関連論文

• Sacoidosis with Membranous Nephropathy and Granulomatous Interstitial Nephritis
• Pathophysiological Role of Magnesium in Familial Bartter's Syndrome.

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