Prevention of Premenstrual Exacerbation of Hereditary Coproporphyria by Gonadotropin-Releasing Hormone Analogue
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概要
- 論文の詳細を見る
A 20-year-old Japanese female needed frequent hospitalization due to premenstrual exacerbation of hereditary coproporphyria (HCP). Intranasal buserelin acetate, a gonadotropin-releasing hormone analogue, was given to suppress her menstrual cycles. Her porphyric symptoms subsided dramatically as she became amenorrhoeic. Urinary excretion of porphyrin derivatives fell significantly. She has been free from recurrent attacks, but suffers a minor porphyric attack once in 5 years. However, borderline osteopenia secondary to hypoestrogenism has been noted. Although these analogues are potent in suppressing estrogen-induced porphyric symptoms, due precautions should be taken to avoid bone demineralization in the long-term use.(Internal Medicine 38: 365-368, 1999)
- 社団法人 日本内科学会の論文
著者
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Asai Masato
The Department Of Internal Medicine The Japanese Red Cross Nagoya First Hospital
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Hasegawa Haruhiko
The Department Of Internal Medicine The Japanese Red Cross Nagoya First Hospital
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Yamamori Ikuo
The Department Of Internal Medicine The Japanese Red Cross Nagoya First Hospital
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Muramoto Akiko
The Department Of Internal Medicine The Japanese Red Cross Nagoya First Hospital
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TANAKA Fumi
The Department of Internal Medicine, the Japanese Red Cross Nagoya First Hospital
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Tanaka Fumi
The Department Of Internal Medicine The Japanese Red Cross Nagoya First Hospital
関連論文
- Prevention of Premenstrual Exacerbation of Hereditary Coproporphyria by Gonadotropin-Releasing Hormone Analogue
- Hereditary Complete Thyroxine-Binding Globulin Deficiency: Identification by T3 Resin Uptake Test and DNA Analysis.