Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4^+ T cells

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CD4^+T cells induced by virus-like particles expressing a major T cell epitope down-regulate IL-5 production in an ongoing immune response to Der p 1 independently of IFN-γ production
Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4^+ T cells
T cells in mice expressing a transgenic human TCRβ chain get positively selected but cannot be activated in the periphery by signaling through TCR
Sonic hedgehog promotes CD4^+ T lymphocyte proliferation and modulates the expression of a subset of CD28-targeted genes

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