Activation of aniline by extracts from plants and induction of chromosomal damages in Chinese hamster ovary cells

スポンサーリンク

概要

• 論文の詳細を見る

• Activation of aniline by plant extracts was studied by a chromosomal damage induction assay in Chinese hamster ovary (CHO) cells in vitro. Extracts from roots of Vicia faba activated aniline and the activation caused increases in chromosomal aberrations (CAs) and endoreduplicated cells (ERCs), but did not cause sister-chromatid exchanges (SCEs). Extracts from Pisum sativum and Lactuca sativa, however, did not activate aniline. All C-hydroxylated metabolites of aniline, o-aminophenol, m-aminophenol and p-aminophenol, induced not only CAs but also SCEs in CHO cells. These results show that the pathway for aniline activation by Vicia extracts is by means other than the C-hydroxylation.

• 日本遺伝学会の論文

著者

• Kanaya Nobuhiro

  Department Of Biology Keio University

• KANAYA Nobuhiro

  Department of Biology, Keio University

関連論文

• P-01. Induction of micronuclei by atrazine in plant root tip cells(Abstracts of the 52nd Annual Meeting of the Society of Chromosome Research)
• Activation of aniline by extracts from plants and induction of chromosomal damages in Chinese hamster ovary cells

スポンサーリンク