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Section Of Genetic′ Engineering Research Center For Genetic Engineering And Cell′ Transplantation To | 論文
- The interface between innate and acquired immunity: glycolipid′ antigen presentation by CD1d-expressing dendritic cells to′ NKT cells induces the differentiation of antigen-specific′ cytotoxic T lymphocytes.
- The essential role of phorbol ester-sensitive protein kinase C′ isoforms in activation-induced cell death of Th1 cells.
- The quantitative and qualitative defect of CD4+CD45RO+′ memory-type T cells are involved in the abnormality of TH1′ immunity in atopic dermatitis patients.
- The critical role of Th1-dominant immunity in tumor′ immunology.
- Functional heterogeneity among bone marrow-derived dendritic′ cells conditioned by Th1- and Th2-biasing cytokines for the′ generation of allogeneic cytotoxic T lymphocytes.
- Potentiation of antitumor effect of NKT cell ligand,′ α-galctosylceramide by combination with IL-12 on lung′ metastasis of malignant melanoma cells.
- Distinct role of antigen-specific T helper type 1 (Th1) and Th2′ cells in tumor eradication in vivo.
- The natural killer T (NKT) cell ligand _-galactosylceramide′ demonstrates its immunopotentiating effect by inducing′ intreleukin (IL)-12 production by dendritic cells and IL-12′ receptor expression on NKT cells.
- Indispensable role for TNF-α and IFN-γ at the effector′ phase of liver injury mediated by Th1 cells specific to′ hepatitis B virus surface antigen.