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Department Of Medicinal Chemistry Center For Frontier Research In Medicinal Science And 21st Century | 論文
- Development of New Photoresponsive Paclitaxel Prodrug
- Phototaxel : Development of First Photoresponsive Prodrug of Paclitaxel via Modification of Phenylisoserine Moiety
- Identification of Calmodulin-Binding Peptides by Partial-Filling Affinity Capillary Electrophoresis with Mass Spectrometric Detection
- Design and Synthesis of Dipeptide-type HIV-1 Protease Inhibitors with High Antiviral Activity
- Design of BACE1 Inhibitors : Replacing the P_1' Residue with Non-Acidic Moiety
- Modification of P4 Position in β-secretase (BACE1) Inhibitors Containing Phenylnorstatine
- Design of β-Secretase (BACE1) Inhibitors with Carboxylic Acid Bioisosteres
- O-N Intramolecular Acyloxy Migration Reaction : from the Prodrug Strategy to the Migration of Protective Groups in Amino Acids
- Design and Synthesis of β-Secretase Inhibitors Containing Hydroxymethylcarbonyl Isostere as a Transition State Mimic
- High-throughput Screening Method for Ligand Peptides Using Capillary Electrophoresis-Mass Spectrometry (CE-MS)
- Design and Synthesis of Inhibitory Peptides against EGF Receptor Dimerization
- Significance of interaction of BACE1-Arg235 with its ligands and design of BACE1 inhibitors
- Design and Synthesis of Highly Active β-Secretase (BACE1) inhibitors, KMI-420 and KMI-429, with Enhanced Chemical Stability
- O-N Intramolecular Acyl and Acyloxy Migration Reaction in the Development of Water-Soluble Prodrugs of Taxoids
- Click Peptide : In Situ Production of pyroGlu-Abeta from the O-Acyl Isopeptide
- Use of O-Acyl Isopeptides to Identify New Functions of Amyloid β Peptides
- Screening Methodology for Discovery of Inhibitory Peptides against Pathogenic Proteins using a Plug-plug Affinity Capillary Electrophoresis Technique
- Design of BACE1 Inhibitors Containing 5-Nitro-Isophthalamide
- Defying Difficult Diseases : Peptide Chemistry in Medicinal Science