HUA Ding | Department of Immunology, Kumamoto University School of Medicine
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概要
Department of Immunology, Kumamoto University School of Medicine | 論文
- Mouse germinal center B cells with the xid mutation retain responsiveness to antimouse CD40 antibodies but diminish IL-5 responsiveness
- BCR signal through α4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation
- Cross-linking of B cell antigen receptorrelated structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase
- NF-κB is required for CD38-mediated induction of C_γ1 germline transcripts in murine B lymphocytes
- Decreased expression of germinal center-associated nuclear protein is involved in chromosomal instability in malignant gliomas