Storb Ursula | Department Of Molecular Genetics And Cell Biology And Biochemistry And Molecular Biology University

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Department Of Molecular Genetics And Cell Biology And Biochemistry And Molecular Biology University | 論文

• The 3' lgκ enhancer contains RNA polymerase II promoters : implications for endogenous and transgenic κ gene expression
• γ2b provides only some of the signals normally given via μ in B cell development
• Ig gene somatic hypermutation in mice defective for DNA polymerase δ proofreading
• The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while lg and BCL6 genes are hypermutated in human memory B cells
• The C_H 1 and transmembrane domains of u in the context of a γ2b transgene do not suffice to promote B cell maturation

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