Miyashita Yoh | Internal Medicine Sakura Hospital Toho University School Of Medicine
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概要
関連著者
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Miyashita Yoh
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Miyashita Yoh
Internal Medicine Sakura Hospital Toho University School Of Medicine
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Shirai Kohji
The Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Shirai Kohji
Department Of Internal Medicine Sakura Hospital Toho University School Of Medicine
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Shirai Kohji
Clinical Laboratory Medicine Department Of Pharmacy Sakura Hospital Toho University School Of Medici
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Miyashita Yoh
Departments Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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KANTOH Shigeru
the Department of Internal Medicine
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Miyashita Yoh
Department Of Internal Medicine Sakura Hospital Toho University School Of Medicine
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Shirai Kohji
Department Of Internal Medicine Sakura Hospital School Of Medicine Toho University
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Shirai Kohji
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Shirai Kohji
Center Of Diabetes Endocrinology & Metabolism Sakura Hospital Toho University School Of Medicine
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MIYASHITA YOH
Department of Internal medicine, Center of Diabetes, Endocrinology, and Metabolism, Sakura Hospital,
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OYAMA Tomokazu
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Miyashita Yoh
Department Of Internal Medicine Sakura Hospital Medical Center Of Toho University
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Oyama Tomokazu
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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SHIRAI Kohji
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Shirai Kohji
Department Of Clinical Laboratory Medicine Sakura Hospital School Of Medicine Toho University
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SAIKI Atsuhito
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Saiki Atsuhito
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Saiki Atsuhito
Center Of Diabetes Endocrinology And Metabolism Sakura Hospital Toho University
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Shimizu Kazuhiro
東邦大学医療センター佐倉病院 循環器センター
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MIYASHITA Yoh
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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Itoh Yoshiaki
Center Of Diabetes Endocrine And Metabolism Sakura Hospital Toho University School Of Medicine
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ENDO Kei
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Endo Kei
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Miyashita Yoh
Center Of Diabetes Endocrinology & Metabolism Sakura Hospital Toho University School Of Medicine
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KOIDE Nobukiyo
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Koide Nobukiyo
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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OYAMA Tomokazu
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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OHIRA Masahiro
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Ohira Masahiro
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Iiduka Takuo
The Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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BAN Noriko
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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SASAKI Hidehisa
Department of Pharmacy, Sakura Medical Center, School of Medicine, Toho University
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MURANO Takeyoshi
Department of Research and Development, Toho University Sakura Medical Center
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MIYASHITA Yoh
Internal Medicine, Toho University, Sakura Hospital, School of Medicine
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SHIRAI Kohji
Internal Medicine, Toho University, Sakura Hospital, School of Medicine
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SAIKI Atsuhito
Center of Diabetes, Endocrinology and Metabolism, Sakura Hospital, School of Medicine Toho Universit
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Yagima Takeshi
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Ban Noriko
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Shirai Kohji
Internal Medicine Sakura Hospital Medical Center Toho University
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Nagayama Daizi
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Murano Takeyoshi
Department Of Research And Development Toho University Sakura Medical Center
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Takeyoshi Murano
Department Of Clinical Laboratory Medicine Sakura Hospital Toho University
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Sasaki Hidehisa
Department Of Pharmacy Sakura Medical Center School Of Medicine Toho University
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Hitsumoto Takashi
Department of Internal Medicine, Toho University Sakura Medical Center
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Takahashi Mao
Department of Internal Medicine, Toho University Sakura Medical Center
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Noike Hirofumi
Department of Internal Medicine, Toho University School of Medicine, Sakura Hospital
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Noike Hirofumi
Toho Univ. School of Medicine. Cardiovascular Diagnostic Laboratory Center
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Yamaguchi Takashi
Department of Cardiology, Saitama Medical School
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Iiduka Takuo
Department Of Cardiology Toyohashi Heart Center
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KOIDE Nobukiyo
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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SHIRAI Kohji
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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Noike Hirofumi
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Noike Hirofumi
Cardiovascular Center Toho University Hospital At Sakura
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KAWANA Hidetoshi
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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SHIRAI Kohji
Clinical Laboratory Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Med
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Hitsumoto Takashi
Department Of Internal Medicine Sakura Hospital Toho University School Of Medicine
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Ozaki Hiroshi
Department Of Internal Medicine Sakura Hospital Toho University School Of Medicine
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Kawana Hidetoshi
Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Noike Hirofumi
Department Of Cardiovasucular Center Sakura Hospital Medical Center Toho University
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Yamaguchi Takashi
Department Of Cardiology Saitama Medical School
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Takahashi Mao
Department Of Cardiovascular Center Toho University Sakura Medical Center
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YAMAMURA Shigeo
School of Pharmaceutical Sciences, Toho University
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ITOH Yoshiaki
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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Irie Minoru
Department Of Internal Medicine School Of Medicine Toho University
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Otsuka Masaki
Center Of Diabetes Endocrinology & Metabolism Sakura Hospital Toho University School Of Medicine
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Yamamura Shigeo
School Of Pharmaceutical Sciences Toho University
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ITOH YOSHIAKI
Department of Internal medicine, Center of Diabetes, Endocrinology, and Metabolism, Sakura Hospital,
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NAGAYAMA Daiji
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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NAGAYAMA Daizi
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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OHHIRA Masahiro
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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KANAI Saburo
Departments of Pharmacy, Toho University, Sakura Hospital School of Medicine
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ITO Yoshiaki
Internal Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Medicine
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TOMIOKA Hisao
Internal Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Medicine
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WATANABE JIN
Clinical Laboratory Medicine,Sakurai Hospital
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Tomaru Takanobu
Cardiology Center Toho University Sakura Hospital
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Tomaru Takanobu
Departments Of Clinical Physiology Sakura Medical Center School Of Medicine Tohoku University
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NAKAMURA Keijiro
Departments of Cardiovascular Center, Sakura Medical Center, School of Medicine, Toho University
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HITSUMOTO Takashi
The Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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Watanabe Jin
Clinical Laboratory Medicine Sakura Hospital Toho University School Of Medicine
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Kanai Saburo
Departments Of Pharmacy Toho University Sakura Hospital School Of Medicine
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Kanai Saburo
Department Of Pharmacy Faculty Of Medicine Sakura Hospital Toho University
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Hitsumoto Takashi
The Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Iizuka Takuo
The Department Of Internal Medicine Sakura Hospital Toho University School Of Medicine
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Tomioka Hisao
Internal Medicine Department Of Pharmacy Sakura Hospital Toho University School Of Medicine
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Nakamura Keijiro
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Itoh Yoshiaki
Department Of Chemistry For Materials Faculty Of Engineering Mie University
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Sakurai Takeshi
Cardiology Center Toho University Sakura Hospital
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Aoyagi Kaneyuki
Department Of Cardiovascular Center Toho University Sakura Hospital
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Takahashi Mao
The Department Of Internal Medicine Sakura Medical Center School Of Medicine Toho University
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Kameda Noriaki
Department of Pathology, Toho University Medical Center Sakura Hospital
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Ozaki Hiroshi
Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, University
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Shirai Koji
Department of Internal Medicine, Toho University Sakura Medical Center
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Iizuka Takuo
Department of Cardiology, Toyohashi Heart Center
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Uchi Takashi
Department of Internal Medicine, Toho University School of Medicine, Sakura Hospital
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Kanai Masahito
Department of Internal Medicine, Toho University School of Medicine, Sakura Hospital
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Oosawa Hidefumi
Toho Univ. School of Medicine. Cardiovascular Diagnostic Laboratory Center
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Shimizu Kazuhiro
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Matsumoto Jun
Department of Geography, University of Tokyo
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Sugiyama Yuukou
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Kinoshita Keisuke
Department of Electrical and Electronics Engineering, Sophia University
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Hirano Keiichi
Department of Applied Physics, Faculty of Engineering, University of Tokyo
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OZAKI Hiroshi
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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OTSUKA Masaki
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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MATSUZAKA Teruyo
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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Irie Minoru
Toho University
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Iiduka Takuo
Department Of Cardiovascular Center Sakura Hospital Medical Center Toho University
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Uchi Takashi
Department Of Cardiovascular Center Sakura Hospital School Of Medicine Toho University
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Ozaki Hiroshi
Department Of Veterinary Pharmacology Graduate School Of Agriculture And Life Sciences The Universit
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Kameda Noriaki
Department Of Pathology Sakura Hospital School Of Medicine Toho University
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Ohsawa Hidefumi
Cardio Vascular Cnter. Toho Universty School Of Medicine Sakura Hospital
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Kanai Masahito
Cardiology Sannnou Hospital
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Sakurai Takeshi
Department Of Pharmacology University Of Tsukuba
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TSUSHIMA TOSHIO
Department of Endocrinology, Clinical Institute of Endocrinology, Tokyo Women's Medical University
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Tomaru Takanobu
Department of Clinical Pyisiology, Toho University Sakura Hospital
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Tsushima Toshio
Department Of Endocrinology Clinical Institute Of Endocrinology Tokyo Women's Medical Universit
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Tsushima Toshio
Department Of Internal Medicine 2 Tokyo Women's Medical University School Of Medicine
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ENDOH Kei
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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SHIRAI Kouji
Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University
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OYAMA Tomokazu
Internal Medicine, Toho University, Sakura Hospital, School of Medicine
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ENDO Kei
Center of Diabetes, Endocrinology and Metabolism, Sakura Hospital, Toho University
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SASAKI Hidehisa
Pharmaceutical Department, Sakura Hospital, Toho University
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EBISUNO Mariko
Center of Diabetes, Endocrinology and Metabolism, Sakura Hospital, Toho University
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OHIRA Masahiro
Center of Diabetes, Endocrinology and Metabolism, Sakura Hospital, Toho University
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TAKEYOSHI Murano
Department of Clinical Laboratory Medicine, Sakura Hospital, Toho University
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WATANABE Hitoshi
Clinical Laboratory Medicine, Sakura Hospital, Toho University School of Medicine
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WATANABE Fusako
Department of Clinical Laboratory, Sakura Hospital, School of Medicine Toho University
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ENDO Kei
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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MIYASHITA Yoh
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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SAIKI Atsuhito
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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OYAMA Tomokazu
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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KOIDE Nobukiyo
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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OZAKI Hiroshi
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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OTSUKA Masaki
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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ITO Yoshiaki
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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SHIRAI Kohji
The Center of Diabetes, Endocrine and Metabolism, Sakura Hospital, Toho University School of Medicin
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WAKABAYASI Kiyoji
Department of Surgery, Sakura Hospital, School of Medicine Toho University
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WATANABE Husako
Center of Diabetes, Endocrinology & Metabolism, Sakura Hospital, Toho University School of Medicine
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YAGIMA Takeshi
Department of pharmachology, Sakura Hospital, Toho University School of Medicine
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HASIGUCHI Shoichiro
Internal Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Medicine
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TOTSUKA Mitsuya
Internal Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Medicine
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AOKI Akiko
Clinical Laboratory Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Med
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KUROKAWA Minoru
Clinical Laboratory Medicine, Department of Pharmacy, Sakura Hospital, Toho University School of Med
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HASHIGUCHI SYOICHIRO
Department of Internal Medicine,School of Medicine,Toho University
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TOTUKA MITUYA
Department of Internal Medicine,School of Medicine,Toho University
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Osawa Hidefumi
Cardiovascular Diagnostic Laboratory Center Toho University School of Med.
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Yoshinaga Kunio
Department of Cardiovascular Center, Toho University Sakura Hospital
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Sugiyama Yuko
Department of Cardiovascular Center, Toho University Sakura Hospital
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Kaku Michihisa
Department of Cardiovascular Center, Toho University Sakura Hospital
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Oosawa Hidefumi
Department of Cardiovascular Center, Sakura Hospital, School of Medicine, Toho University
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MURANO Takeyoshi
Clinical Laboratory Medicine, Sakura Hospital, School of Medicine, Toho University
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Tomaru Takanobu
Department Of Cardiology Toho University Sakura Hospital
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MIKAMO Hiroshi
Departments of Cardiovascular Center, Sakura Medical Center, School of Medicine, Toho University
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NAKAGAMI Takahiro
Departments of Cardiovascular Center, Sakura Medical Center, School of Medicine, Toho University
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SUZUKI Masayo
Departments of Cardiovascular Center, Sakura Medical Center, School of Medicine, Toho University
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Watanabe Fusako
Department Of Clinical Laboratory Sakura Hospital School Of Medicine Toho University
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Watanabe Husako
Center Of Diabetes Endocrinology & Metabolism Sakura Hospital Toho University School Of Medicine
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Kurokawa Minoru
Clinical Laboratory Medicine Department Of Pharmacy Sakura Hospital Toho University School Of Medici
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Shimizu Kazuhiro
Department Of Dermatology Nagasaki University Graduate School Of Biomedical Sciences
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Kinoshita Keisuke
Department Of Electrical And Electronics Engineering Sophia University
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Matsumoto Jun
Department Of Cardiovascular Center Toho University Sakura Hospital
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Sugiyama Yuko
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Sakurai Takeshi
Department Of Chemistry Faculty Of Science Kanazawa University
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Sakurai Takeshi
Cardiovascular Center Toho University Hospital At Sakura
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Aoki Akiko
Clinical Laboratory Medicine Department Of Pharmacy Sakura Hospital Toho University School Of Medici
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Takano Toru
2nd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo Tokyo
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Shirai Kouji
Department Of Internal Medicine Sakura Hospital Medical Center Toho University
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Urano Yosuke
Clinical Laboratory Medicine Sakura Hospital Toho University School Of Medicine
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Hirano Keiiti
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Kaku Michihisa
Department Of Cardiovascular Center Toho University Sakura Hospital
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Suzuki Masayo
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Totuka Mituya
Department Of Internal Medicine School Of Medicine Toho University
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Osawa Hidebumi
Cardiovascular Diagnostic Laboratory Center Toho University School Of Medicine
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Mikamo Hiroshi
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Ebisuno Mariko
Center Of Diabetes Endocrinology And Metabolism Sakura Hospital Toho University
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Kanai Masahito
Cardiovascular Center Toho University Medical Center Sakura Hospital
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Shirai Koji
Department Of Clinical Laboratory Medicine Sakura Hospital School Of Medicine Toho University
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Yoshinaga Kunio
Cardiovascular Center Toho University Hospital At Sakura
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Oosawa Hidefumi
Cardiovascular Laboratory Center Toho University School Of Medicine
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Tomaru Takanobu
Clinical Physiology, Sakura Medical Center, School of Medicine Toho University
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Tomaru Takanobu
Second Department Of Internal Medicine University Of Tokyo School Of Medicine
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Murano Takeyoshi
Clinical Laboratory Medicine Sakura Hospital School Of Medicine Toho University
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Osawa Hidefumi
Cardiovascular Diagnostic Lavoratory Center
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Nakagami Takahiro
Departments Of Cardiovascular Center Sakura Medical Center School Of Medicine Toho University
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Takano Toru
Second Department Of Internal Medicine University Of Tokyo School Of Medicine
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Sakurai Takeshi
Department Of Chemistry Division Of Material Sciences Graduate School Of Natural Science And Technol
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Kanai Masahito
Cardiovascular Center Toho University Hospital At Sakura
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Kanai Masahito
Department Of Cardiology Toho University Medical Center Sakura Hospital
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Ozaki Hiroshi
Department Of Electronic Engineering Faculty Of Engineering Osaka University
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Totsuka Mitsuya
Internal Medicine Department Of Pharmacy Sakura Hospital Toho University School Of Medicine
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Hasiguchi Shoichiro
Internal Medicine Department Of Pharmacy Sakura Hospital Toho University School Of Medicine
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Wakabayasi Kiyoji
Department Of Surgery Sakura Hospital School Of Medicine Toho University
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Sakurai Takeshi
Department Of Cardiology Toho University Medical Center Sakura Hospital
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Matsumoto Jun
Department Of Biology Keio University
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Matsuzaka Teruyo
Center Of Diabetes Endocrinology & Metabolism Sakura Hospital Toho University School Of Medicine
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Tomaru Takanobu
Clinical Physiology Sakura Medical Center School Of Medicine Toho University
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Matsumoto Jun
Department Of Applied Chemistry Tokyo Metropolitan University
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Hashiguchi Syoichiro
Department Of Internal Medicine School Of Medicine Toho University
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Watanabe Hitoshi
Clinical Laboratory Medicine Sakura Hospital Toho University School Of Medicine
著作論文
- Atorvastatin and Pravastatin Elevated Pre-heparin Lipoprotein Lipase Mass of Type 2 Diabetes with Hypercholesterolemia
- Oxysterol-Induced Apoptosis of Vascular Smooth Muscle Cells is Reduced by HMG-CoA Reductase Inhibitor, Pravastatin
- Complications in Adults with Growth Hormone Deficiency : A Survey Study in Japan
- Effects of Olmesartan, an Angiotensin II Receptor Blocker, and Amlodipine, a Calcium Channel Blocker, on Cardio-Ankle Vascular Index (CAVI) in Type 2 Diabetic Patients with Hypertension
- Protective Effects of Efonidipine, a T- and L-Type Calcium Channel Blocker, on Renal Function and Arterial Stiffness in Type 2 Diabetic Patients with Hypertension and Nephropathy
- Effects of Pitavastatin, a 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, on Cardio-Ankle Vascular Index in Type 2 Diabetic Patients
- A Case of Obstructive Jaundice with Severe Hypercholesterolemia Probably Due to Lipoprotein-Y
- Effect of Acarbose, an Alpha-Glucosidase Inhibitor, on Serum Lipoprotein Lipase Mass Levels and Common Carotid Artery Intima-Media Thickness in Type 2 Diabetes Mellitus Treated by Sulfonylurea
- Effects of Calorie-Restricted Low-Carbohydrate Diet on Glucose and Lipid Metabolism in Otsuka Long Evans Tokushima Fatty Rats
- Effect of Combination Therapy of Benidipine Hydrochloride and Candesartan Cilexetil on Serum Lipid Metabolism and Blood Pressure in Elderly Hypertensive Patients with Type 2 Diabetes Mellitus
- The Role of Pitavastatin-Enhanced Lipoprotein Lipase Expression in 3T3-L1 Preadipocytes
- Probucol and Atorvastatin Decrease Urinary 8-Hydroxy-2'-deoxyguanosine in Patients with Diabetes and Hypercholesterolemia
- Enhancement of MMP-9 Activity in THP-1 Cells by 7-ketocholesterol and Its Suppression by the HMG-CoA Reductase Inhibitor Fluvastatin
- Usefulness of Preheparin Lipoprotein Lipase Mass as a Parameter for Predicting the Efficacy of Colestimide
- Pitavastatin Enhanced Lipoprotein Lipase Expression in 3T3-L1 Preadipocytes
- Apoptosis Induced by 7-Ketocholesterol is Enhanced in Smooth Muscle Cells Derived from OLETF Rats
- Reduction of Visceral Adiposity After Operation in a Subject with Insulinoma
- Effect of Deposited Lipids in Atheromatous Lesions on the Migration of Vascular Smooth Muscle Cells
- Effect of Temocapril Hydrochloride on Serum Lipid Levels in Patients with Hypertensive Type 2 Diabetes Mellitus
- The Effect of Growth Hormone Secreted by Mild Exercise on Fatty Acid Mobilization in Patients with Diabetes Mellitus
- Low preheparin serum lipoprotein lipase mass is an independent risk factor for acute myocardial infarction
- Association between Cardio-Ankle Vascular Index and Serum Cystatin C Levels in Patients with Cardiovascular Risk Factor
- Cardio-Ankle Vascular Index is a Candidate Predictor of Coronary Atherosclerosis
- Cardio-ankle vascular index is a candidate for useful indicator of evaluation of arterial wall stiffness
- Clinical Significance of Plasma 7-ketocholesterol Concentrations in Patients with Coronary Artery Disease (Atherosclerosis, Clinical 13 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Clinical Significance of Plasma 7-ketocholesterol Concentrations in Patients with Coronary Vasospastic Angina Pectoris(Angina Pectoris, Basic/Clinical 6 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Cytotoxicity of Some Oxysterols on Human Vascular Smooth Muscle Cells was mediated by apoptosis