KUBOTA Hirokazu | Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd.,

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Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. III. Synthesis of (±)-N-[2-(3,4-Dichlorophenyl)-4-(spiro-substituted piperidin-1'-yl)butyl]-N-methylbenzamides and Evaluation of NK_1-NK_2 Dual Antagonistic Activities
Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. I. Design and Synthesis of (±)-N-[2-(3,4-Dichlorophenyl)-4-(spiro[isobenzofuran-1(3H), 4'-piperidin]-1'-yl)butyl]-N-methylbenzamide, YM-35375,as a New Lead Compound for Novel Neurokinin Rec
Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. II. Syntheses and NK_2 Receptor-Antagonistic Activities of N-[2-Aryl-4-(spiro-substituted piperidin-1'-yl)butyl]carboxamides
Disulfide linkages in a heat-stable enterotoxin (STP) produced by a porcine strain of enterotoxigenic Escherichia coli.

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