Early ambulation after total knee arthroplasty prevents patients with osteoarthritis and rheumatoid arthritis from developing postoperative higher levels of D-dimer

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This study aimed to clarify the therapeutic effects of postoperative ambulationafter total knee arthroplasty (TKA) on deep venous thrombosis (DVT) in patients withosteoarthritis (OA) and rheumatoid arthritis (RA) after TKA. Subjects of this study werethirty-seven inpatients (21 inpatients : OA, 16 inpatients : RA) undergoing TKA (32 femaleand 5 male). Subjects were divided into two groups, deep venous thrombosis (DVT) group(n=25) and non-DVT group (N group, n=12). The cutoff value was 10.0 g/ml plasma Ddimerlevel measured on 7th postoperative day. The N group was below the cutoff value.Another cutoff value divided into two groups, ambulatory group (n=26) and non-ambulatorygroup (n=11). Ambulatory group was the date of ambulation beginning below 7thday. Statistical analysis confirmed that all subjects showed a significant correlation tothe date of ambulation. Postoperative ambulation beginning had strong association withthe level of D-dimer (r=0.71). Group comparison showed that the non-ambulatory grouphad significant higher values of D-dimer than ambulatory group (P=0.022). Typical casesupported these results. Postoperative early ambulation within a week after TKA keptpatients with OA and RA after TKA lower level of D-dimer.