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- 2005-12-24
論文 | ランダム
- Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner
- Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22
- Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
- Tuberous sclerosis complex (TSC) gene involvement in sporadic tumours
- Insulin activation of RheB, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2