Effects of Improved Microchannel Structures on the Separation Characteristics of Microchip Capillary Electrophoresis
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概要
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We fabricated the electrophoresis microchips using the UV polymerization technique. We employed plastic substrates that were suitable for rapid prototyping instead of glass and quartz. A thick UV negative photo resist was used to form molds and poly-dimethylsilozane (PDMS) was polymerized by a thermal curing process on the mold to obtain replica microchips. Electroosmotic flow (EOF) was measured to evaluate the surface. Rhodamine B and sulforhodamine B are successfully separated using the microchip. Characteristic differences between UV-fabricated and SR-fabricated microchips were evaluated by EOF measurement. It was observed that accurately defined microchannels fabricated by synchrotron radiation (SR) lithography show constant peak heights and FWHMs. Thus the advantage of the application of SR lithography to the mold fabrication is also demonstrated.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2003-06-15
著者
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Hattori Tadashi
Laboratory Of Advanced Science And Technology For Industry
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Utsumi Yuichi
Laboratory Of Advanced Science And Technology For Industry
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Ozaki Motoaki
Faculty Of Science Himeji Institute Of Technology
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Terabe Shigeru
Faculty of Science, Himeji Institute of Technology, 3-2-1 Koto, Kamigori, Ako, Hyogo 678-1205, Japan
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TERABE Shigeru
Faculty of Science , Himeji Institute of Technology
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Ozaki Motoaki
Faculty of Science, Himeji Institute of Technology, 3-2-1 Koto, Kamigori, Ako, Hyogo 678-1205, Japan
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HATTORI Tadashi
Laboratory of Advanced Science & Technology for Industry, University of Hyogo
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