In-Vivo Imaging of Cancer Implanted in Nude Mice by Two-Crystal Interferometer-Based Phase-Contrast X-Ray Computed Tomography
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概要
- 論文の詳細を見る
Using the wave nature of X-rays, in-vitro phase-contrast X-ray imaging can clearly reveal the detailed inner structures of cancer in human and rabbit. In this study, using a newly developed imaging system with a two-crystal interferometer and the Fourier data acquisition technique, we presented, for the first time, in-vivo phase-contrast X-ray computed tomography (CT) images of cancer implanted in nude mice. The two-crystal interferometer, which helps to eliminate the distortion of the half mirror of an X-ray interferometer due to the heat from live animals, was the key device for successful in-vivo imaging. CT images obtained using the Fourier technique were available in approximately 40 min while the animal was still under anesthesia.
- Japan Society of Applied Physicsの論文
- 2004-09-15
著者
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Hyodo Kazuyuki
High Energy Accelerator Research Organization
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Yoneyama Akio
Advanced Research Laboratory Hitachi Ltd.
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Lwin Thet
Graduate School Of Comprehensive Human Science Institute Of Clinical Medicine University Of Tsukuba
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Takeda Tohoru
Graduate School Of Comprehensive Human Science Institute Of Clinical Medicine University Of Tsukuba
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Tsuchiya Yoshinori
Graduate School Of Comprehensive Human Sciences University Of Tsukuba
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Wu Jin
Graduate Institute of Pharmaceutical Chemistry, China Medical University
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Takeda Tohoru
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan
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Hyodo Kazuyuki
High Energy Accelerator Research Organization, Tsukuba, Ibaraki 305-0801, Japan
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Wu Jin
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan
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Yoneyama Akio
Advanced Research Laboratory, Hitachi, Ltd., Hatoyama, Saitama 350-0395, Japan
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