Molecule Manipulation at Electrified Interfaces using Metal Nanogates

スポンサーリンク

概要

• 論文の詳細を見る

• Previously documented results on molecule manipulation using metal nanogates are comprehensively reviewed to conclude novel characteristics, which could be widely used for the developments of the systems at electrified interfaces. Novel systems to segregate molecules from self-spreading lipid bilayers in electrolyte solutions have been developed by using metal nanogate structures on solid surfaces. The spatial distribution of target molecules in the lipid bilayer changes depending on the molecule characteristics, such as charge, size, and flexibility. Energy dissipation during the spreading of the molecules on the surface contributes to the compression of the lipid bilayer at the nanogate, leading to the formation of a gradient of the electrochemical potential of the bilayer system including the target molecule in the vicinity of the nanogate (<100 nm from the gate). The gradient results in a segregation force being applied to target molecules in the order of 10−15 N per molecule. The segregation property can be tuned by changing the electrolytes, lipid molecules, temperature, and the width and surface hydrophobicity of the metal nanogate. Introduction of asymmetry to the nanogate leads to further effective diffusion control in a direction perpendicular to the spreading. It has been demonstrated that target molecules with a different number of glycolipid per protein in the lipid bilayer are effectively separated based on the Brownian ratchet mechanism.

• 公益社団法人 電気化学会の論文

著者

• Murakoshi Kei

  Department Of Chemistry Graduate School Of Engineering Science Osaka University

• Nabika Hideki

  Department Of Chemistry Graduate School Of Science Hokkaido Univ.

• Takimoto Baku

  Department Of Chemistry Graduate School Of Science Hokkaido Univ.

• MOTEGI Toshinori

  Department of Chemistry, Faculty of Science, Hokkaido University

関連論文

• 2P-176 ブラウニアン・ラチェット機構に基づく二次元分子分別システムの構築(生体膜・人工膜-ダイナミクス,第47回日本生物物理学会年会)
• Electrochemical Potential Control of Stretched Length of Au Nano-wire in Solution
• New Approach to Lowering of the Overvoltage for Oxygen Evolution on RuO_2 and Related Metal-Oxide Electrodes by Ion Implantation
• 2P-238 自発展開脂質二分子膜上でのタンパク会合体拡散挙動の単一分子追跡(生体膜/人工膜・ダイナミクス,第46回日本生物物理学会年会)
• 1P-226 自発展開脂質二分子膜を分子キャリアとしたナノフィルターの構築(生体膜/人工膜・構造物性,第46回日本生物物理学会年会)
• Tracking Single Molecular Diffusion on Glass Substrate Modified with Periodic Ag Nano-architecture
• Conductance Characteristics of Ni Nanoconstrictions Prepared in Solution
• Electric-field-assisted Control of Lipid Bilayer Stacking Structure
• Molecule Manipulation at Electrified Interfaces using Metal Nanogates

スポンサーリンク