メニエール病の蝸電図所見:グリセロール・テストとの比較

概要

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Mechanical difference of both positive findings between transtympanic electrocochleography and the glycerol dehydration test was discussed in sixty-three patients with Meniere's disease. The pure tone audiometry was measured before and after intravenous drip infusion of 50 g glycerol in forty-five ears. Transtympanic electrocochleography was recorded in sixty-five ears. Both measurements were carried out at ten days to twenty years from onset of the first episodic attack. The results were as follow: 1) Electrocochleographic positive findings, significant enlargement of -SP/AP ratio, was recorded in 63% of sixty-five ears. This incidence increased in cases with pure tone average of 40 dB or more and two or more years from onset (p < 0.10). 2) Significant improvement of hearing threshold following infusion of glycerol was showed in 56% of forty-five ears. This incidence increased in cases with pure to ne average of less than 40 dB and less than two years from onset (p<0.10). 3) Those who showed negative findings of both measurements was 7% of all. This results indicate that electrocochleography and the glycerol dehydr a tion test should be measured together in clinical practice. Because the former was more useful in relative advanced Ménière's disease, and in the early stage of Meniere's disease the latter was more effective.
耳鼻咽喉科臨床学会の論文