Pathological study on buried gallbladder in patients with gallbladder carcinoma
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概要
- 論文の詳細を見る
We sometimes encounter a buried gallbladder in patients with gallbladder carcinoma. If the buried gallbladder is defined as over one third of the gallbladder buried into the liver, it was found in 4 out of 6 autopsied cases and 2 of 13 extended cholecystectomized cases with gallbladder carcinoma, respectively, but not in 9 controlled cases. These buried gallbladder cases were associated with directly metastasized carcinoma to the liver which showed both tumor necrosis and fibrosis in various degrees. Fibrosis was immunopositive for α-smooth muscle actin, a marker of myofibroblasts. The elastic fiber layer of hepatic capsule was destroyed in the buried gallbladder cases, while well-preserved in the 9 controlled cases.<BR>Tumor necrosis plays a role in decreasing tumor volume and myofibroblasts have contraction ability. Therefore, a buried gallbladder might appear after occurrence of gallbladder carcinoma.
- Japan Biliary Associationの論文
Japan Biliary Association | 論文
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