Comparison of Gold-PAMAM and Gold-PPI Dendrimer Nanocomposites for Antioxidant Action
スポンサーリンク
概要
- 論文の詳細を見る
Gold-dendrimer nanocomposites were prepared in the presence of poly (amidoamine) (PAMAM) dendrimer (generation 3, 3.5, 5, and 5.5) or poly (propyleneimine) (PPI) dendrimer (generation 3 and 4) via reduction of HAuCl<SUB>4</SUB> with sodium borohydride. The average particle sizes of the gold nanoparticles were independent of the dendrimer concentration as well as the dendrimer generation, ranging between 3.0 and 4.3 nm in diameter for PAMAM dendrimers and between 2.1 and 2.3 nm in diameter for PPI dendrimers. The catalytic activities of the gold-dendrimer nanocomposites upon elimination of hydroxyl radicals formed in an H<SUB>2</SUB>O<SUB>2</SUB>/FeSO<SUB>4</SUB> system was examined using a spin-trapping method. The catalytic activity of gold-PPI dendrimer nanocomposites was slightly lower than that of gold-PAMAM dendrimer nanocomposites. In addition, the gold-dendrimer nanocomposites exhibited high catalytic activities which were hardly affected by the concentration as well as the generation of the dendrimer except PAMAM dendrimer 3.5. The highest activity for the gold-PAMAM dendrimer G3.5 nanocomposites was 85 times that of ascorbic acid.
- Japan Society of Colour Materialの論文