Serum Serotonin Elevated Cartinoid Tumor of the Larynx
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概要
- 論文の詳細を見る
Carcinoid tumor of the larynx is a rare and malignant neoplasm. It is reported that a case of laryngeal carcinoid tumor in a 74 year old male was located on the surface of the epiglottis with one-sided neck metastasis. He died of multiple metastasis; lung, heart, aorta, pancreas, gallbladder, skin and posterior peritoneal space when 9 months had passed after surgical treatment of suprahemilaryngectomy and one-sided radical neck dissection.<BR>The serum level of serotonin was elevated when lung metastasis was detected. This high level of serotonin was decreased by the chemotherapy of cis-platinum (CDDP) and 5-fluorouracil (5-FU).<BR>It was reported that carcinoid tumors of the larynx were aggressive and malignant with distant metastasis but not with serotonin elevation. Our case suggests that the tumor volume of distant metastasis may increase the serum level of serotonin and that CDDP+5-FU may be effective therapy for this tumor before and/or after surgery.
- The Japan Laryngological Associationの論文
The Japan Laryngological Association | 論文
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