Late Development of Laryngeal Cancer in Previously Irradiated Larynx
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概要
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Five cases of recurrent laryngeal cancer, occurring 5 or more years after having radiotherapy for the treatment early glottic cancer of the larynx, are reported.<BR>Case I received irradiation for glottis T1aN0 of the left vocal cord. Thirteen years later, a total laryngectomy was performed for cancer of the right vocal cord extending to the subglottis.<BR>Case II received irradiation for glottis T1aN0 of the right vocal cord. Thirteen years later, reradiation was performed for cancer of the right vocal cord and false cord. Ultimately, a total laryngectomy was required and performed three years after the re-radiation.<BR>Case III received irradiation for glottis T1aN0 of the left vocal cord. Nine years later, an emergency tracheotomy followed by a total laryngectomy was performed for a subglottic tumor.<BR>Case IV received irradiation for glottis T1aN0 of the left vocal cord. Five years and 4 months later, glottis T2N0 of the left vocal cord was detected. The patient expired of progressive prostate cancer.<BR>Case V received irradiation for anterior subglottis T1N0. Eight years later, a total laryngectomy was performed for glottis T3N0 of the left vocal cord.<BR>There are three possible causes for carcinogenesis for these cases : late recurrence (persistence of the original carcinoma), radiation induced cancer and multicentric cancerization. Long-term followup seems to be necessary even with early stage laryngeal cancer patients.
- The Japan Laryngological Associationの論文
The Japan Laryngological Association | 論文
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