A STUDY OF FAILIAL AGGREGATION OF SERUM URIC ACID LEVELS IN TOOSHI ISLAND, JAPAN, 1975
スポンサーリンク
概要
- 論文の詳細を見る
The analysis of familial ag g r e gation was carried out on the residents in Tooshi island, Mie prefecture, closed community in which outdoor environmental factors are expected to be uniform. The standardized serum uric acid value called "normal quotient" of serum uric acid value were used for the sake of comparative study. This study suggests that gene action may be caused by so called polygene system. In addition to polygenic inheritance, the value of serum uric acid is also influenced by the interaction of genetic and environmental factors. In the parent-chi l d r en analysis, the most consistent relationship was. found in mother and child. There was no significant aggregation of serum uric acid values between spouses, although there was very significant aggregation between siblings. The extent of aggregation of serum uric acid values between siblings was not significantly different from that of mother and child. Consequently, our present study lends further weight to the view that serum uric acid values are influenced mainly by mothers' genetic factors.
- Japanese Society of Gout and Nucleic Acid Metabolismの論文
Japanese Society of Gout and Nucleic Acid Metabolism | 論文
- Superoxide Generation by Neutrophilis Stimulated by Synovial Fluid of Gouty Arthritis and the Effects of Allopurinol and Colchicine
- Clinical Value of the Measurement of Uric Acid in CSF in Patients with Cerebral Diseases: Part III.:Postoperative Course with Ruptured Aneursm
- Serum Concentration of Uric Acid in Long-distance and Marathon Runner
- Responses in Blood Pressure and Purine Nucleotide Degradaion During Exercise in Patients with Essential Hypertension
- The clinical significance of hypouricemia of in-patients and out-patients