関節リウマチ患者における手術と機能回復

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概要

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• Objective: We identified 225 rheumatoid arthritis (RA) patients who required surgery after failure to prevent joint destruction by drug therapy alone, and we analyzed postoperative functionality on the basis of a questionnaire survey.Methods: We recruited 157 of 225 RA patients who required joint replacement, fixation, or arthroplasty in the upper and lower extremities to participate in this study. The mHAQ (modified health assessment questionnaire) wasused to assess their physical condition and the Fujibayashi classification was usedt or neasure functional improvernent of the upperand lower extremities aftersurgery. We also assessed the impactof the number of joints treated on physical function and the influence of the length of the postoperative period on functional improvement and physical status.Results: No significant postoperative improvement in function of the upper extremities was identified at follow-up. By contrast, significant improvement was reported in the lower extremities according to the Fujibayashi classification more than ten years after surgery. The changes assessed by the mHAQ showed significant improvement with in ten years of surgery, but not there after. Significant improvement according to the mHAQ was seen both for ≦2 and ≧3 joints.Conclusions: To improve the quality of life of RA patients it is therefore recormnended that surgical intervention is performed earlier to maintain better physical status and functionality of the upper and lower extremities.

• 日本関節病学会の論文

日本関節病学会 | 論文

• 関節リウマチ患者における手術と機能回復
• 低出力超音波刺激(LIPUS)および線維芽細胞増殖因子(FGF-2)の骨形成促進作用におけるヒアルロン酸(HA)の影響
• 変形性関節症に対するグルコサミン・コンドロイチンの有用性 (第36回[日本関節病]学会寄稿)
• 人工膝関節再置換術の経験--脛骨結節骨切り術の適応と合併症について
• RA頚椎病変に対する上位頚椎後方除圧固定術の治療成績と問題点

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