若年発症した難治性再発性多発軟骨炎例
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概要
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Relapsing polychondritis (RP) is a comparatively rare chronic inflammation which occurs in systemic cartilage such as the auricula, nose and trachea. Those tissues become denatured and are irreversibly destroyed. RP is more commonly seen in the case of middle-aged patients, and is treated with steroids and immunosuppressants. We report herein on a case of RP that developed in a 16-years-old male. The patient showed various symptoms such as respiratory tract inflammation, auricular chondritis, saddle nose, vertigo, and hearing loss. He was diagnosed as having RP one month after the onset, but the disease proved recalcitrant even with repeated steroid pulse therapy and the use of several kinds of immunosuppressant. We have found RP very difficult to treat in this patient because his symptoms are aggravated with doses of predonisolone less than 27.5 mg.
- 耳鼻咽喉科臨床学会の論文
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