A case of Paget's disease of bone with bisphosphonate-related osteonecrosis of the jaws (BRONJ) that could have been observed for a long term after sequestrectomy
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We report a case of Paget's disease of bone with bisphosphonate-related osteonecrosis of the jaws (BRONJ) that was could have been observed for a long term after sequestrectomy. A 60-year-old woman was referred to our hospital in November 2004 with because she the had complaints ed of both the spontaneous pain of the left maxilla and the malodor of the mouth. Intraoral findings at the initial visit revealed a the defect of the alveolar gum from the left upper second premolar to the left maxillotuberosity and the sequestrum at the same site.Her face showed a typical features of the characteristic of Paget's disease of bone. Her midfacial unit was appeared forward and her chin was retreated. Radiographic views of the skull remarkably revealed a remarkable cotton-wool appearance, and the left maxilla in the orthopantomography was occupied with by many radiopaque images mixed with some radiolucent lesions that might have been sequestrum. CT scans showed that the maxilla was totally gross and the left side of the cortical bone had been abnormally absorbed. We performed the sequestrectomy of the left maxilla under general anesthesia in February 2005. This patient took had taken various some kinds of bisphosphonates for the Paget's disease of bone from November 2000 to September 2010. We finally diagnosed of the present case as Paget's disease of bone with BRONJ. This case received could have been performed a long- term follow- up after the surgical treatment for BRONJ. No signs of recurrence and or appearance of new lesions have been noted for six years since after the surgical treatment.
- 特定非営利活動法人 日本口腔科学会の論文
特定非営利活動法人 日本口腔科学会 | 論文
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