EFFECTS OF DIFFERENT MODES OF LOW LEVEL LASER IRRADIATION ON THE HEALING OF EXPERIMENTALLY INFECTED WOUNDS
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概要
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Many studies, using low level laser irradiation (LLLI), have been performed to investigate the influence of laser irradiation on the healing process of wounds or lesions. It has been proposed that the low incident levels of laser irradiation may stimulate the growth of bacterial cells and normal tissue cells. This study was performed to determine whether LLLI has a promotive effect on the healing of experimentally infected wounds and which irradiation type has the more promotive healing effect in the rat model. The most and least proliferative pulses found effective in a previous study were used in this study. The laser was a pulsed gallium arsenide (GaAs) semiconductor laser with a wavelength of 904 nm. The incident average powers were 1 mW and 10 mW. Circular, full-thickness skin defects measuring about 6 mm in diameter were produced on the gluteus superficialis of both hind limb in each rat. Staphylococcus aureus was inoculated on the wounds. In addition to comparing the two pulsing frequencies, irradiation around the periphery of the wound was compared with irradiation of the wound bed. The wound contraction rate was measured after irradiation accoring to irradiation and pulse types. There was a significant increase in wound contraction rates in the irradiation groups for both pulse types compared with the unirradiated contralateral control wounds. Comparing the healing effects of peripheral and wound bed irradiation, however, there was no significant difference between the effects of the two irradiation types.
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