Factors Affecting the Effect of Treatment of VCM Based on the Quantity of MRSA for Hospital-Acquired Pneumonia
スポンサーリンク
概要
- 論文の詳細を見る
Objective: To determine the factors affecting the antimicrobial effect of VCM on MRSA.Study Design: Case series study.Methods: This study was conducted on pneumonia patients admitted to a university-affiliated hospital between January 2000 and December 2008 and had MRSA in their sputum culture. From seven days prior to the starting VCM administration through the end of the administration, detailed information such as underlying diseases, VCM serum concentration and quantity of MRSA were recorded. Logistic regression analysis was carried out on current diseases, trough concentration, surgery experience, and the detection of Gram-negative bacteria to verify the antimicrobial effect of VCM.Results: The number of subjects investigated this study was 55 subjects. Multiple logistic regression analysis did not yield any significant factors when carried out using the factors affecting the antimicrobial effect of VCM on MRSA as independent variables.Conclusions: Multivariable analysis yielded no factors as being significant in affecting the antimicrobial effect of VCM, but did indicate in that patients aged 70 and older, the antimicrobial effect of VCM was poor for MRSA. This suggests that when pharmacists intervene in antimicrobial treatment for improved effects, it is important to consider not only the serum concentration of VCM, but also the background of the patient.
- 日本医薬品情報学会の論文
日本医薬品情報学会 | 論文
- 一般用医薬品の添付文書理解度調査法の開発:―理解度への影響因子の検討―
- 汎用データベースソフトを用いた持参薬識別システムの構築と有用性の検討
- 実務実習生の医薬品情報リテラシー向上を目的とした医薬品情報実習の効果
- 医療用および一般用医薬品を対象としたドーピング防止早見表の作成
- Preparation of Quick Reference Table on Incompatibilities of Injections for Use in the ICU and Investigation of the Usefulness of This Table