キャピラリー電気泳動法の法薬毒物分析への応用

概要

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Capillary electrophoresis (CE) is now widely used as a separation and detection technique, due to its high peak resolution and simple operation. Since the analytical equipment had been commercialized in the early 1990's, CE has been introduced to the field of forensic toxicology. Various CE methods have been developed, such as simultaneous drug detection and chiral analysis of drugs and metabolites, and applied to real forensic examination. This review surveys the status of presentations on CE techniques in forensic toxicology, and introduces the CE methods performed in the author's laboratory for forensic examination on poisoning cases. The authors propose the practical use of CE in forensic toxicology as a means of a simple screening method for toxic substances, and quantification for target compounds or counter cations of hazardous anionic compounds by taking advantage of CE methods in simplicity, rapidity, quantification accuracy and wealth of separation conditions.
日本法科学技術学会の論文