抗血小板抗体陽性の再生不良性貧血と脳内出血　　大量血小板輸注・摘ひ・開頭術にて救命し得た１小児例:—大量血小板輸注・摘脾・開頭術にて救命し得た1小児例—

概要

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Antiplatelet iso-antibody and massive intracerebral hemorrhage (lt. occipital area) developed to a nine year old boy 12 months after the diagnosis of idiopathic aplastic anemia. Since there was no longer appreciable increase of platelet on ordinary platelet transtusions and there were no HLA matched donors for platelet transfusion, he was splenectomized to improve the effect of platelet transfusion, as suggested by Flatow and Freireich. Soon after the splenectomy, craniotomy and evacuation of intracerebral hematoma were performed successfully. After splenectomy, recovery rate of the platelets transfused was 48.7±29.5% (mean±1 S. D.). Although he is still pancytopenic, he has been in good condition and attending school for 12 months after the splenectomy and craniotomy.
一般社団法人日本血液学会の論文