脂肪塞栓症候群による急性肺障害に好中球エラスターゼ阻害剤とステロイド剤が有効であった一例
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An 83-year-old female with hip joint fracture developed severe dyspnea and was admitted to our hospital. On admission, her blood gas analysis indicated hypoxemia. Her chest radiograph showed a ground-grass pattern in bilateral lung fields and enlargement of right atrium. The level of neutrophil elastase activity was elevated. She was diagnosed as post embolism syndrome. A treatment with sodium sivelestat hydrate, a neutrophil elastase inhibitor, intravenously, was started at the second hospital day. The level of neutrophil elastase activity returned to normal after the treatment. Her respiratory condition was improved. We experienced that a case of post embolism syndrome was improved by treating with neutrophil elastase.
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