Anti-hyperglycemic effects of plum in a rat model of obesity and type 2 diabetes, Wistar fatty rat
スポンサーリンク
概要
- 論文の詳細を見る
Dried plums, considered a healthy food in the West and used as medicine in India, contain phenolic compounds with protective actions against age-related diseases. Effects of oral plum ekisu (concentrated juice) on lipid and glucose tolerance were assessed in insulin-resistant obese Wistar fatty rats. Plum ingestion decreased blood glucose (P < 0.05) and plasma triglyceride concentrations (P < 0.01) compared with controls. Plum treatment for 2 weeks reduced areas under the curve (AUCs) for glucose and insulin during a glucose tolerance test. In db/db mice, plum decreased these AUCs, and also blood glucose during an insulin tolerance test. Plum treatment significantly increased plasma adiponectin concentrations and PPARγ mRNA expression in adipose tissue from Wistar fatty rats. Plum thus may increase insulin sensitivity in these rats via adiponectin-related mechanisms.
- バイオメディカルリサーチプレスの論文
バイオメディカルリサーチプレス | 論文
- Methylseleninic acid (MSA) inhibits 17β-estradiol-induced cell growth in breast cancer T47D cells via enhancement of the antioxidative thioredoxin/ thioredoxin reductase system
- Expression of human factors CD81, claudin-1, scavenger receptor, and occludin in mouse hepatocytes does not confer susceptibility to HCV entry
- Effect of heat on synthesis of gelatinases and pro-inflammatory cytokines in equine tendinocytes
- Histological observations on the microenvironment of osteolytic bone metastasis by breast carcinoma cell line
- Effect of inducible nitric oxide synthase on apoptosis in Candida-induced acute lung injury