Inhibitory Effect of Long Term 1.ALPHA.-Hydroxyvitamin D3 Administration on Helicobacter pylori Infection
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概要
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The effects of long-term supplementation with 1α-hydroxyvitamin D3 (1α (OH) D3) on serum pepsinogen (PG) I levels, and Helicobacter pylori (H. pylori) infection rate, were investigated in healthy elderly women, aged 70 to 99 years, in a nursing home. Of these 34 subjects, 15 have been administered one microgram of 1α (OH) D3 daily for twenty years, because of osteoporosis treatment, and 19 were free from the drug. Serum PG-I levels and H. pylori infection rate in subjects with 1α (OH) D3 were significantly lower than those without treatment (p<0.05). These results suggested the inhibitory effect of long-term administration of 1α (OH) D3 on H. pylori infection.
- 日本酸化ストレス学会 JCBN事務局の論文
日本酸化ストレス学会 JCBN事務局 | 論文
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