閉塞型睡眠時無呼吸症候群に伴う睡眠時の多発性心室性期外収縮が口腔内装置治療によって消失した１症例

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This is a report of a 47-yo female patient who had been suffering from obstructive sleep apnea(OSAS) concomitant with frequent ventricular premature complexes(VPCs) during sleeping which might lead to sudden death. Standard polysomnography(PSG) revealed her OSAS with apnea-hypopnea index(AHI) of 14.7, the longest apnea time(LAT) of 83.5 sec, nadir SpO<SUB>2</SUB> of 81%, and snoring index(SI) of 295.1. Frequent VPCs(total of 763 times) were also observed during the PSG. Oral appliance(ORAP) therapy was applied to her OSAS because she could not tolerate nasal continuous positive airway pressure previously applied elsewhere. The PSG under ORAP therapy showed the improvements of OSAS(AHI of 0.6, LAT of 22.3sec, nadir SpO<SUB>2</SUB> of 93%, SI of 0.1) as well as the disappearance of frequent VPCs.
日本循環制御医学会の論文