ヒト骨転移バイオマーカーの発見と臨床応用

概要

論文の詳細を見る
The leading cause of death in our country has been cancer since 1981. The total number of deaths from cancer reached 304,286, with a mortality rate of 241.5 per 100,000, accounting for 31.0% of all deaths in 2002. According to an estimate prepared by the Foundation for Promotion of Cancer Research (2003), it is expected that 890,000 people will contract cancer each year. Bones are located next to the lungs and liver, and bone is a favorite site for cancer metastasis. Bone metastasis is found in 25 to 50% of terminal cancer patients, and it is thought that 70000 to 150000 terminal-stage cancer patients are presently suffering from bone metastasis. Maintaining the QOL of these patients is an urgent concern in order to help them live fulfilling lives. The authors therefore apply medical technology to identify bone metastasis molecular target proteins using proteomics in order to facilitate low cost early diagnosis and prevention of bone metastasis.
西日本整形・災害外科学会の論文