Influence of the extent of aortic replacement on survival and quality of life in patients with aortic root replacement
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Background: The influence of the extent of aortic replacement on the aortic root replacement is unclear. We investigatedthe clinical outcomes of the aortic root replacement in terms of the extent of aortic replacement and evaluated quality of life(QOL) after surgery. Methods: Thirty six patients were enrolled in this study. The mean age was 59.0 ± 13.1 years. The 36 patients were dividedinto three groups according the extent of aortic replacement: 21 patients with replacement of the ascending aorta (SB), 7 patientswith hemi-arch replacement (HB), and 8 patients with total aortic arch replacement (TB). Postoperative health-relatedQOL was evaluated by SF-36 Version 2. Results: The hospital mortality in the 36 patients was 2.8%. The patient (TB) died from fungal infection of the prostheticgraft. Three late deaths (8.6%) were observed: cerebral hemorrhage in one (SB), pneumonia in one (SB), and unknown in one(HB). The 5-year survival was 94.1 ± 5.7% in the SB group, 100% in the HB and 87.5 ± 11.7% in the TB groups, respectively(p=0.84). One patient (4.8%) in the SB group had an aorta-related event 7 years after surgery. No patinets had aorta-relatedevents in both the HB and the TB groups. There was no significant difference in postoperative health-related QOL among thethree groups. Conclusions: Aortic root replacement at our hospital achieved excellent results. Neither long-term survival nor postoperativeQOL differed significantly according to the extent of aortic root replacement. We plan to extend the present study by includinga larger number of subjects.
- 長崎大学医学部の論文
長崎大学医学部 | 論文
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