Central Hypothyroidism with Severely Delayed Myelination in a Boy Born to a Mother with Untreated Graves' Disease
スポンサーリンク
概要
- 論文の詳細を見る
We report a 2-year old boy with central hypothyroidism accompanied by delayed myelination, born to a mother with untreated Graves' disease. His mother was diagnosed as having Graves' disease 6 days after delivery. At 3 months of age he was diagnosed as having central hypothyroidism, and L-thyroxine replacement therapy was started. His psychomotor development was delayed and magnetic resonance imaging of the brain showed severely delayed myelination. At 2 years of age serum thyrotropin responses to thyrotropin-releasing hormone were still blunted. Whether his central hypothyroidism is permanent or ultimately reversible remains to be determined, but it is possible that hypothyroxinemia in the neonatal period may interrupt the myelination of the brain.
- 日本小児内分泌学会の論文
日本小児内分泌学会 | 論文
- 43 Common origin of the Q258X mutation in StAR gene responsible for congenital aderenal lipoid hyperplasia in Japanese
- Recent Change in the Annual Incidence of Childhood Type 2 Diabetes in the Tokyo Metropolitan Area
- A Case of Acute Lymphoblastic Leukemia with Prader-Willi Syndrome during Growth Hormone Therapy
- Characteristics of a Fulminant Onset Form of Idiopathic Type 1 Diabetes Mellitus in Japanese Children
- Different Skeletal Phenotypes in a Mother and Two Daughters with Short Stature Homeobox-Containing Haploinsufficiency