ヒト声帯粘膜上皮の分化に関する電顕的研究

概要

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The differentiation processes of the vocal cord mucosa in human fetuses have been studied only by light microscopy. So we studied the vocal cord mucosa in human fetuses (at gestational ages from 10th to 21st week) by scanning and transmission electron microscopies and could disclose more detailed features of cytodifferentiation of this mucosa. These results and the review of the literatures lead to the following conclusions: 1. We could demonstrate for the first time that primary cilia appear in the vocal cord mucosa of human fetuses. 2. Ciliated cells were observed on the vocal cord of the fetal life in human as well as animals. And the ciliogenesis was found to be same as the previous reports. 3. The formation of plicae on the surface of the vocal cord was due to the overgrown mucosa of the ventricle, and the mucosa caudal to these plicae possessed the features as the squamous epithelium which is proper to the vocal cord. 4. Glycogen granules in non-ciliated cells decreased in parallel with the differentiation of the cells, suggesting that they provide a source of energy necessary for the cell differentiation.
耳鼻と臨床会の論文