:—Imaging of <SUP>201</SUP>Tl in the extravascular space—
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概要
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<I>In order to evaluate</I> <SUP>201</SUP>Tl-<I>accumulation in lung, </I> <SUP>201</SUP>Tl <I>imaging was performed using a scintillation camera coupling to a small digital computer, and blood clearance of it was examined.</I><BR><I>After the injection of 74 MBq (2mCi) of</I> <SUP>201</SUP>Tl-<I>chloride, the serial images and static images were obtained. In order to obtain the image of</I> <SUP>201</SUP>Tl <I>in the extravascular space [T<SUB>E</SUB> (x, y) ], a subtraction technique was performed as follows; after 2 anterior views of</I> <SUP>201</SUP>Tl <I>were obtained using a 20% window centered at 80 keV [T<SUB>0</SUB> (x, y) ] and 140 keV [T<SUB>140</SUB> (x, y) ] respectively, and blood sample was taken, radionuclide angiocardiography with 185 MBq (5 mCi) of</I> <SUP>99m</SUP>Tc-<I>human serum albumin and it's static image were done in the same supine position and blood sample was taken too. The radioactivity of</I> <SUP>201</SUP>Tl<I> (T) and</I> <SUP>99m</SUP>Tc<I> (HB) in the blood was counted by a autogamma scintillation counter. Then the image of T<SUB>E</SUB> (x, y) was obtained by the following formula; </I><BR><I>T<SUB>E</SUB> (x, y) =T<SUB>0</SUB> (x, y) - [H (x, y) -T<SUB>140</SUB> (x, y) ] T<SUB>B</SUB>/H<SUB>B</SUB>.</I><BR><I>Following results were obtained; </I><BR><I> (1) The disappearance of</I> <SUP>201</SUP>Tl <I>from the blood was rapid and 15 min after the injection only 10-15% of the activity after 1 min was present in the blood.</I><BR><I> (2) The lung activity in the time activity curve decreased rapidly to reach plateau within 100-150 sec after the injection.</I><BR><I> (3) The image of</I> <SUP>201</SUP>Tl <I>in the extravascular space was nearly equal to the original one as regard to the radioactivity of</I> <SUP>201</SUP>Tl <I>in lung.</I>
- 社団法人 日本アイソトープ協会の論文
社団法人 日本アイソトープ協会 | 論文
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