A 3-Month-Old Boy with Rhabdoid Tumor of Spinal Cord Origin.
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We reported a 3-month-old boy with malignant rhabdoid tumor (MRT) of spinal cord origin. He was admitted to our hospital because of paralysis of the left lower extremity, which had started several days before admission. A magnetic resonance image (MRI) of his spinal cord showed a mass at the Th10-L 1 level. T 1-and T2-weighted MRI showed an isointense mass, and a Tl-weighted MRI with contrast medium demonstrated enhancement. The tumor could not be excised because the intradural extramedullary yellowish-white mass had infiltrated into the medulla, and a biopsy specimen was taken. Histological examination showed that the tumor was composed of round cells with prominent nuclei and eosinophilic cytoplasmic inclusion. Immunoperoxidase stains were positive only for vimentin. Electron microscopy and cytogenetics were not examined. In spite of intensive chemotherapy, he had multiple metastasis in the brain, and he died 5 months after the beginning of the symptoms. Primary MRT of CNS is uncommon. MRT of the spinal cord is especially rare, and the present case is only the second reported in the literature.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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