A Case of Postoperative Brain and Spinal Metastases from Rectal Cancer Successfully Treated with Oxaliplatin/fluorouracil/leucovorin
スポンサーリンク
概要
- 論文の詳細を見る
Metastatic brain tumors are generally treated with radiotherapy because many anticancer drugs cannotcross the blood-brain barrier. We report a case of postoperative brain and spinal metastases from rectal can cer treated with oxaliplatin/fluorouracil/leucovorin (modified FOLFOX-6). A 49-year-old-man underwent Miles. operation with D2 lymphadenectomy for type 2 rectal cancer and segmental resection for liver metastasis. Nine months later, the patient underwent a surgery for cerebellar metastasis during treating with oral uracil and tegafur (UFT) following 5-fluorouracil/leucovorin. He then underwent gamma knife therapy for brain metastases and surgical resection for spinal metastasis 20 months after the first operation and 11 months after cerebellar metastasis surgery. Modified FOLFOX-6 was started thereafter due to recurring brain metastases and residual spinal metastasis. One year later, target lesions were evaluated as making a partial response based on response evaluation criteria in solid tumors (RECIST) and no more new metastases had developed as of this wrinting.
- 一般社団法人 日本消化器外科学会の論文
一般社団法人 日本消化器外科学会 | 論文
- A Case of Traumatic Injury of the Retrohepatic Inferior Vena Cava with Severe Liver Rupture.
- Cytoprotective Action of Co-enzyme Q10 and Ulinastatin on the Ischemic Damage of the Liver Following in Vivo Cold Infusion
- A Case Report of Lesser Omental Cyst.
- The Significance of Resection Range and Surgical Margin for Hepatocellular Carcinomas.
- Post transfusion hepatitis in heapatectomized patients.