The Influence of Mixed Histologic Type within a Primary Colorectal Cancer on Lymph Node Metastasis.
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概要
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This study, which included 330 cases of advanced colorectal cancer, assessed the effects of mixed histologic types within primary cancer on the lymph node metastatic rate. We investigated the histologic type contained in primary cancer with a high lymph node metastatic rate, and the nodal metastatic rates of each histologic type depending on their volume within primary cancer. Cancer which contained a poorly differentiated histologic type as a minor subpopulation within the primary cancer (73%) had a significantly higher nodal metastatic rate than cancer without mixed histologic types (48%) (p<0.05). When primary cancer contained the poorly differentiated or mucinous histologic type as a minor subpopulation, the nodal metastatic lesion usually contained the histologic type of a major subpopulation and seldom contained the poorly differentiated (23%) or mucinous (16%) histologic type. From these results, it was considered that the condition which promotes the development of the poorly differentiated histologic type within a primary cancer is important in lymph node metastasis in cancer with mixed histologic types.
- 一般社団法人 日本消化器外科学会の論文
一般社団法人 日本消化器外科学会 | 論文
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