Diabetic Patient with "Takotsubo"-Like Cardiomyopathy Followed by Guillain-Barre Syndrome.
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A 70-year-old woman hospitalized for muscular weakness in the extremities was found in electrocardiography on admission to have ST-segment elevation in leads II, III, aVF and V<SUB>1</SUB> through V<SUB>4</SUB>, and inverted Twaves were seen in II, III, aV<SUB>F</SUB> and V<SUB>2</SUB> to V<SUB>6</SUB>. Although no stenotic lesion was detected in emergency coronary angiography, left ventriculography showed a hypokinetic area around the apex with an ejection fraction of 31%. <SUP>123</SUP>I-MIBG myocardial scintigraphy showed an extensive defect around the apex. These findings supported a diagnosis of "Takotsubo" -like cardiomyopathy.<BR>Forty days after admission, albuminocytogenic dissociation of cerebrospinal fluid led us to diagnose Guillain-Barré syndrome as responsible for the weakness in the extremities.<BR>Guillain-Barré syndrome may damage the sympathetic nervous system, so we concluded that abnormality of the cardiac sympathetic nervous system due to Guillain-Barré syndrome and diabetic autonomic neuropathy caused cardiac dysfunction. Diabetes complicated "Takotsubo" -like cardiomyopathy followed by Guillain-Barré syndrome is extremely rare.
- 一般社団法人 日本糖尿病学会の論文
一般社団法人 日本糖尿病学会 | 論文
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