タイトル無し
スポンサーリンク
概要
- 論文の詳細を見る
Hamster islet cells were employed as a target of islet cell surface antibodies (ICSA) in comparison with rat islet cells by the indirect method of immunofluorescence, since the preparation of islet cells is more feasible with the hamster than with the rat. ICSA-positive sera against rat islet cells were obtained from two insulin-dependent diabetic patients (Cases 1 and 2) and a nondiabetic adult. (Case 3). In Case 1, the percentage of positively stained cells was 70% with hamster islet cells and 59% with rat islet cells. In Case 2, the figunes were 54% and 69%, and, in Case 3, they were 50% and 58%, while the normal healthy control showed 11% and 6%, respectively.<BR>Reactivity against islet cells was also compared in these sera with that against spleen cells originated from the identical animal. Serum from Case 1 showed equally high percentages in both islet cells and spleen cells. In Case 2, the percentage of positively stained islet cells was high, although the stainability of spleen cells was low, indicating the presence of organ-specific antibody. In Case 3, high stainability was observed against both types of cells. This is probably due to the injection of anti-diphtheria horse serum received about 20 years ago, which might cause the production of heterogeneous ICSA against rat islet cells.
- 一般社団法人 日本糖尿病学会の論文
一般社団法人 日本糖尿病学会 | 論文
- Hyperlipidemia and Analysis of the Use of Lipid-lowering Drugs in Non-insulin-dependent Diabetes Mellitus.
- Thyrotoxic Crisis in a Patient with Mitochondrial Diabetes Mellitus.
- Rapidly Progressive Nephropathy in a Young Patient with Mitochondrial Gene Mutation.
- An Autopsy Case of Ketoacidosis in Insulin Dependent Diabetes Mellitus Patient Complicated with Adult Respiratory Distress Syndrome, DIC and Leukopenia.
- Studies on Alcoholic Beverages in Relation to Body Weight for Mild Diabetics